Journal of the American Chemical Society

Direct and reverse addition reactions of nitriles with lithium aluminum hydride in ether and in tetrahydrofuran

LM Soffer, M Katz

Index: Soffer; Katz Journal of the American Chemical Society, 1956 , vol. 78, p. 1705,1706

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Citation Number: 28

Abstract

The reductions of nitriles in ether and in tetrahydrofuran at various hydride-nitrile ratios have been investigated, using both direct and reverse addition procedures. The various reduction products include primary amines, aldehydes, hydrogen, 1, 3-diamines (resulting from dimerization) and other higher products. Reaction sequences are proposed for the major processes in both types of reaction. No evidence was obtained for the presence of a ...