Direct Synthesis of Diverse β??Fluoroethylamines by a Multicomponent Protocol

…, S Tanaka, TE Thomas, N Ganesh…

Index: Prakash, G. K. Surya; Gurung, Laxman; Jog, Parag V.; Tanaka, Shinji; Thomas, Tisa Elizabeth; Ganesh, Nimisha; Haiges, Ralf; Mathew, Thomas; Olah, George A. Chemistry - A European Journal, 2013 , vol. 19, # 11 p. 3579 - 3583

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Citation Number: 5

Abstract

Multicomponent reactions (MCRs) are synthetically highly efficient and economical as they offer high structural diversity and incorporate molecular units of all reaction components in a single step.[1] A well-known example of an MCR is the Mannich reaction, in which the educts formaldehyde, an amine, and a ketone or aldehyde are converted directly into the adduct bearing the molecular fragments of all components. It has been established as a ...