Reactions of polyfluorinated chalcones with o-aminobenzenethiol and its zinc salt

…, NA Orlova, IV Beregovaya, VV Shelkovnikov

Index: Shmuilovich; Orlova; Beregovaya; Shelkovnikov Russian Chemical Bulletin, 2011 , vol. 60, # 2 p. 361 - 367

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Citation Number: 4

Abstract

Abstract The reactions of polyfluorochalcones with o-aminothiophenol in methanol in the presence of HCl afford polyfluorine-substituted 2, 3-dihydrobenzo [b][1, 5] thiazepines. In some cases, the cyclization is accompanied by fluorine substitution in the perfluorophenyl ring. Probably, the formation of thiazepines proceeds through the Michael thia-adduct. The Zn salt of o-aminothiophenol reacts with chalcones in DMF exclusively via fluorine ...