Utilization of α, γ-Dialkoxyacetoacetates in the Synthesis of Certain 2-Thiouracils and Uracils1

HR Henze, EN Kahlenberg

Index: Henze; Kahlenberg Journal of the American Chemical Society, 1958 , vol. 80, p. 1664

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Citation Number: 5

Abstract

In light of the early interest in thiouracils3 and~ racils,~ and more recently, in connection with a study of compounds of possible use as metabolic inhibitors, it was decided to attempt the synthesis of certain pyrimidines containing alkoxy substituents. ized through utilizat. ion of well-established proccdures involving Condensation of substituted acctoacetates with thiourea or urea. During the ireliininary investigations in this work, it was dcnionstrated ...