Synthesis and β-adrenoblocking activity of 1-dibenzofuranyloxy-3-aminopropan-2-ols

…, LA Zhmurenko, ÉK Orlova, VA Zagorevskii

Index: Glozman, O. M.; Ismailov, Sh. I.; Borisova, L. N.; Zhmurenko, L. A.; Orlova, E. K.; Zagorevskii, V. A. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 10 p. 687 - 692 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 10 p. 1193 - 1198

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Abstract

A whole series of B-adrenoblockers has been developed among the heterocyclic derivatives of l-aryloxy-3-aminopropan-2-ols (AAP). Thus, in the series of benzofuran derivatives of AAP B-adrenoblocking agents were discovered having bicyclic (befunalol) and tricyclic structures (butocrolol, a furochromone derivative)[7, 8].