(H+, K+)-ATPase inhibiting 2-[(2-pyridylmethyl) sulfinyl] benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The …

B Kohl, E Sturm, J Senn-Bilfinger…

Index: Journal of Medicinal Chemistry, , vol. 35, # 6 p. 1049 - 1057

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Citation Number: 77

Abstract

... 1050 Journal of Medicinal Chemistry, 1992, Vol ... antisecretory activity of the PSBs is believed to be exerted by covalent modification of one or more thiol groups on the acidic lumenal side of the en~yme.~ Recently, welo and others" established the chemical transformations that ...