Direct arylations on water: synthesis of 2, 5-disubstituted oxazoles balsoxin and texaline

SA Ohnmacht, P Mamone, AJ Culshaw…

Index: Ohnmacht, Stephan A.; Mamone, Patrizia; Culshaw, Andrew J.; Greaney, Michael F. Chemical Communications, 2008 , # 10 p. 1241 - 1243

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Citation Number: 64

Abstract

The functionalisation of heteroaromatic compounds by transition metal (TM) catalysed C–C bond formation complements classic condensation chemistry as a strategy for polyfunctional heteroaromatic synthesis. 1 Whereas classic heterocyclic synthesis frequently involves the preparation of appropriately substituted acyclic precursors which undergo cyclocondensation as a final step, TM-catalysed cross couplings offer the possibility of ...