Letters in Organic Chemistry

Lipases Aided Esterification of (2, 2-Dimethyl-1, 3-dioxolan-4-yl) methanol

A Zniszczol, KZ Walczak

Index: Zniszczol, Aurelia; Walczak, Krzysztof Z. Letters in Organic Chemistry, 2014 , vol. 11, # 1 p. 6 - 12

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Citation Number: 2

Abstract

Racemic solketal (2, 2-Dimethyl-1, 3-dioxolan-4-yl) methanol 1, was treated with carboxylic acids of varying chain length or their vinyl esters in the presence of different lipases. The esterification reaction was carried out in n-hexane or diisopropyl ether as a solvent. The yield of the solketal esters and their enantiopurity were satisfactory, as indicated by gas chromatography using chiral column. Lipases from Rhizopus oryzae and Pseudomonas ...