Synthesis and antiinflammatory activity of acyl substituted benzodioxa heterocycles and o-dialkoxybenzenes

VK Daukshas, PG Gaidyalis, LK Labanauskas…

Index: Daukshas, V. K.; Gaidyalis, P. G.; Labanauskas, L. K.; Udrenaite, E. B.; Gasneravichene, G. A.; Raguotene, N. V. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 4 p. 322 - 324 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 4 p. 435 - 437

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Citation Number: 2

Abstract

Among aroyl and cinnamoyl substituted 1, 4-benzodioxanes and 1, 5-benzodioxepanes, compounds having antiinflammatory activity are found [3, 4]. Therefore, with the purpose of studying the relationship between chemical structure and biological activity, and also of searching for new medicines, we have synthesized and investigated the hitherto unknown benzodioxa heterocycles (I-IV) and their acylic analogs, the o-dialkoxybenzenes (V, Vl). l\ ...