Iron-Catalyzed Suzuki− Miyaura Coupling of Alkyl Halides
T Hatakeyama, T Hashimoto, Y Kondo…
Index: Hatakeyama, Takuji; Hashimoto, Toru; Kondo, Yoshiyuki; Fujiwara, Yuichi; Seike, Hirofumi; Takaya, Hikaru; Tamada, Yoshinori; Ono, Teruo; Nakamura, Masaharu Journal of the American Chemical Society, 2010 , vol. 132, # 31 p. 10674 - 10676
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Citation Number: 129
Abstract
In the presence of novel iron (II) chloride− diphosphine complexes and magnesium bromide, lithium arylborates react with primary and secondary alkyl halides to give the corresponding coupling products in good to excellent yields. High functional group compatibility is also demonstrated in the reactions of substrates possessing reactive substituents, such as alkoxycarbonyl, cyano, and carbonyl groups.
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