Facile synthesis of 2-unsubstituted benzofuran-3-carboxylates using diazo (trimethylsilyl) methylmagnesium bromide
Y Hari, R Kondo, K Date, T Aoyama
Index: Hari, Yoshiyuki; Kondo, Ryosuke; Date, Koji; Aoyama, Toyohiko Tetrahedron, 2009 , vol. 65, # 42 p. 8708 - 8713
Full Text: HTML
Citation Number: 15
Abstract
Benzofuran is a promising pharmacophore for drug discovery and a large number of synthetic methodologies for its derivatives have been developed. 1 However, the synthetic approaches to 2-unsubstituted benzofuran-3-carboxylates are limited, 2, 3, 4, 5, 5a, 5b and 5c while there are many methods for the synthesis of 2-substituted ones. 6, 6a, 6b, 6c, 6d, 6e, 6f, 6g, 6h and 6i The methods applicable to the synthesis of various 2-unsubstituted derivatives are only ...
Related Articles:
Convenient method of synthesizing 3-ethoxycarbonyl indoles
[Dudley, Matthew E.; Morshed, Monzur; Brennan, Courtney L.; Islam, M. Shahidul; Ahmad, M. Syarhabil; Atuu, Mary-Rose; Branstetter, Bryan; Hossain, M. Mahmun Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7599 - 7608]
Novel N′-benzylidene benzofuran-3-carbohydrazide derivatives as antitubercular and antifungal agents
[Telvekar, Vikas N.; Belubbi, Anirudh; Bairwa, Vinod Kumar; Satardekar, Kalpana Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 6 p. 2343 - 2346]
The naturally occurring coumarins
[Chatterjea, J. N.; Singh, K. R. R. P. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1053 - 1056]