Hydantoin derivatives as non-peptidic inhibitors of Ras farnesyl transferase

J Lee, J Kim, JS Koh, HH Chung, KH Kim

Index: Lee, Jinho; Kim, Jonghyun; Koh, Jong Sung; Chung, Hyun-Ho; Kim, Kyoung-Hee Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1954 - 1956

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Citation Number: 15

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 1,3,5,5- Tetrasubstituted 2,4-imidazolinedione (hydantoin) derivatives were evaluated as Ftase inhibitors. Potent Ftase inhibitors without thiol or peptide were obtained in three steps. ... 1,3,5,5-Tetrasubstituted 2,4-imidazolinedione (hydantoin) derivatives were evaluated as ...