Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1

S Castellano, A Spannhoff, C Milite…

Index: Journal of Medicinal Chemistry, , vol. 55, # 22 p. 9875 - 9890

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Citation Number: 13

Abstract

... Journal of Medicinal ... Zoo, Laboratory of Medicinal Chemistry, ulica Ogrodowa 2A, 05−092 Lomianki/Kielpin, Poland. ... we replaced the hydroxynaphthalene moiety with the bioisosteric indole framework, a “privileged” structural motif commonly found in pharmaceutical drugs and ...