Journal of the American Chemical Society

Reactions of Vanillin and its Derived Compounds. XXI. 1 Amides of Vanillic and 3-Ethoxy-4-hydroxybenzoic Acids2, 3

IA Pearl, DL Beyer

Index: Pearl; Beyer Journal of the American Chemical Society, 1953 , vol. 75, p. 2627,2628

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Citation Number: 4

Abstract

N-Substituted amides of vanillic acid and 3-ethoxy-4-hydroxybenzoic acid were prepared by condensing the 0-carbethoxy chlorides of these acids with the appropriate amines and selectively hydrolyzing the 0-carbethoxy group of the resulting 0-carbethoxyamides. The compounds were tested for activity against Bacillus mycoides and a large number of pathogenic bacteria and fungi. In general, the attivity was poor and, unlike the esters of ...