Total synthesis of (-)-ptilocaulin

WR Roush, AE Walts

Index: Roush; Walts Journal of the American Chemical Society, 1984 , vol. 106, # 3 p. 721 - 723

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Citation Number: 50

Abstract

722 J. Am. Chem. Soc., Vol. 106, No. 3, 1984 establish the stereochemistry of C-3a and C- 8b relative to C-Sa. We assumed from the outset that control of these centers would be crucial to the success of the plan. In practice, however, the center at C-8b proved to be of little strategic importance since the natural product possesses the thermodynamically most stable configuration at this center.