The Journal of Organic Chemistry

Synthesis of catalpalactone

KJ Lane, AR Pinder

Index: Lane, Kimberley J.; Pinder, A. R. Journal of Organic Chemistry, 1982 , vol. 47, # 16 p. 3171 - 3172

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Citation Number: 8

Abstract

phthalide in which the substituent is a good Ieaving group. The lactone was obtained by reduction of commercial 5, 5-dimethyl-2-pentenolactone, by Baeyer-Villiger oxidation of 2, 2- dimethylcyclopentanone (3), 3 and from 2-methyl-3-buten-2-01 by ethyl cyanoacetate addition followed by hydrolysis and lact~ nization.~ The Baeyer-Villiger reaction was expected to furnish the desired lactone on mechanistic ground^.^ We first chose 3- ...