Tetrahedron Letters

Asymmetric alkylation of 5-alkyl-2-aminothiazolones using a C 2-symmetric chiral tetraamine base

MJ Frizzle, RR Nani, MJ Martinelli, GA Moniz

Index: Frizzle, Matthew J.; Nani, Roger R.; Martinelli, Michael J.; Moniz, George A. Tetrahedron Letters, 2011 , vol. 52, # 43 p. 5613 - 5616

Full Text: HTML

Citation Number: 3

Abstract

... For a recent application of (R,R)-8 in the asymmetric alkylation of arylacetic acids, see J. Am. Chem. Soc., 133 (2011), p. 11936. ... 3; The initial disclosure of this work can be found in: Moniz, GA; Frizzle, MJ; Bernard, C.; Martinelli, MJ; Faul, MM; Nani, RR; Larrow, JF PCT Int. Appl. WO2009002445, 2008. This reference also describes the synthesis of 2. 4; MJ Frizzle, S. Caille, T. Marshall, K. McRae, G. Guo, S. Wu, MJ Martinelli, GA Moniz; ...