Analogs of pteroylglutamic acid. VII. 2-Alkylamino derivatives

B Roth, JM Smith Jr, ME Hultquist

Index: Roth et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 2864,2867

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Citation Number: 21

Abstract

June, 1951 2-ALKYLAMINO DERIVATIVES OF PTEROYLGLUTAMIC ACID 2865 4-amino-6, 7-dimethylpteridines. The 2-dimethylamino analogs of I and I1 were prepared by modifications of the Waller reaction, using 2, 3-dibromopropanal, p-aminobenzoylglutamic acid, and the appropriate 2-dimethylamino-5, 6-diaminopyrimi-dines. Purification was accomplished by methods similar to those previously described. Majima6 reported that the ...