A novel asymmetric benzoin reaction catalyzed by a chiral triazolium salt. Preliminary communication
D Enders, K Breuer, JH Teles
Index: Enders, Dieter; Breuer, Klaus; Teles, J. Henrique Helvetica Chimica Acta, 1996 , vol. 79, # 4 p. 1217 - 1221
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Citation Number: 215
Abstract
Abstract Using the chiral triazolium salt 1 as catalyst, a novel asymmetric variant of the benzoin reaction is reported. For the first time, the scope of the method is extended to a broader range of aromatic aldehydes 2, affording the acyloins 3a–h in yields of 22–72% and enantiomeric excesses up to 86%.
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