Synthesis of avenic acid A and 2′-deoxymugineic acid, amino acids possessing an iron chelating activity
S Fushiya, Y Sato, S Nakatsuyama, N Kanuma…
Index: Fushiya, Shinji; Sato, Yoshikazu; Nakatsuyama, Shuichi; Kanuma, Norio; Nozoe, Shigeo Chemistry Letters, 1981 , p. 909 - 912
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Citation Number: 11
Abstract
Avenic acid A (1), an amino acid derivative possessing an iron chelating activity and excreted from the root of Avena sativa L. was synthesized in optically active form by successive reductive coupling of protected L-aspartic β-semialdehyde and L-malic semialdehyde with L-homoserine lactone. 2′-Deoxymugineic acid (2), a related substance was also synthesized by the same method by which the stereostructure of this amino acid ...
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