Microbial hydroxylation of estrone and estradiol in the 6β-, 7α-, and 15α-positions

AI Laskin, P Grabowich, B Junta…

Index: Laskin,A.I. et al. Journal of Organic Chemistry, 1964 , vol. 29, p. 1333 - 1336

Full Text: HTML

Citation Number: 24

Abstract

The stereospecific hydroxylation of steroidal substrates by microbial enzymes has during the past decade developed into one of the most important and widely employed reactions in steroid chemistry. It has been applied to a large variety of substrates particularly those possessing the pregnane and androstane skeleton, and with very few exceptions all available positions of the steroid nucleus have been hydroxylated by this elegant ...