Liebigs Annalen der Chemie

Synthetic microbial chemistry, XXIII. Synthesis of optically active virginiae butanolides A, B, C, and D and other autoregulators from streptomycetes

K Mori, N Chiba

Index: Mori, Kenji; Chiba, Naoki Liebigs Annalen der Chemie, 1990 , # 1 p. 31 - 37

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Citation Number: 10

Abstract

Abstract Optically active A-factor (1), the factor from Streptomyces viridochromogenes (2), the factors from S. bikiniensis and S. cyaneofuscatus (3–5), and virginiae butanolides A (6), B (7), C (8), and D (9) were synthesized starting from (S)-(−)-paraconic acid (10). The absolute configurations of virginiae butanolides A and C were deduced to be (2S, 3R, 1′ R).