Hydrogen atom adducts to the amide bond. Generation and energetics of amide radicals in the gas phase

…, DD Stephens, F Tureček

Index: Syrstad, Erik A.; Stephens, Daniel D.; Turecek, Frantisek Journal of Physical Chemistry A, 2003 , vol. 107, # 1 p. 115 - 126

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Citation Number: 73

Abstract

The 1-hydroxy-1-(N-methyl) aminoethyl radical (1) represents a simple model system for hydrogen atom adducts to the amide bond in gas-phase peptide and protein ions relevant to electron capture dissociation (ECD). Radical 1 was generated in the rarefied gas phase by femtosecond electron transfer to the stable cation prepared by selective O-protonation of N- methylacetamide. The main dissociations of 1 were loss of the hydroxyl hydrogen atom ...