Esterification of 3, 5-Dimethyl-1-phenylpyrazol-4-ylacetic acid
…, AA Sahakyan, AE Akopyan, LA Sahakyan…
Index: Attaryan, O. S.; Sahakyan, A. A.; Akopyan, A. E.; Sahakyan, L. A.; Asratyan, G. V. Russian Journal of General Chemistry, 2012 , vol. 82, # 9 p. 1610 - 1612,3 Zhurnal Obshchei Khimii, 2012 , vol. 82, # 9 p. 1575 - 1577
Full Text: HTML
Citation Number: 0
Abstract
The ortho-disubstituted phenylacetic acids in whose structure the carboxy group is not directly connected to the benzene ring are easier subjected to esterification in comparison with the ortho-disubstituted benzoic acids. Previously [1] we studied the esterification with methanol of ortho-disubstituted pyrazole-4-ylcarboxylic acid. This acid as an analog of ortho- disubstituted benzoic acid was shown to be not esterified.
Related Articles:
2-(1H-Pyrazol-4-yl) acetic acids as CRTh2 antagonists
[Andres, Miriam; Bravo, Monica; Buil, Maria Antonia; Calbet, Marta; Castro, Jordi; Domenech, Teresa; Eichhorn, Peter; Ferrer, Manel; Gomez, Elena; Lehner, Martin D.; Moreno, Imma; Roberts, Richard S.; Sevilla, Sara Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3349 - 3353]
2-(1H-Pyrazol-4-yl) acetic acids as CRTh2 antagonists
[Andres, Miriam; Bravo, Monica; Buil, Maria Antonia; Calbet, Marta; Castro, Jordi; Domenech, Teresa; Eichhorn, Peter; Ferrer, Manel; Gomez, Elena; Lehner, Martin D.; Moreno, Imma; Roberts, Richard S.; Sevilla, Sara Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3349 - 3353]
2-(1H-Pyrazol-4-yl) acetic acids as CRTh2 antagonists
[Andres, Miriam; Bravo, Monica; Buil, Maria Antonia; Calbet, Marta; Castro, Jordi; Domenech, Teresa; Eichhorn, Peter; Ferrer, Manel; Gomez, Elena; Lehner, Martin D.; Moreno, Imma; Roberts, Richard S.; Sevilla, Sara Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3349 - 3353]