Highly selective directed hydrogenation of enantiopure 4-(tert-butoxycarbonylamino) cyclopent-1-enecarboxylic acid methyl esters
…, MC Lloyd, SJC Taylor, DA Chaplin, R McCague
Index: Smith, Mark E.B.; Derrien, Nadine; Lloyd, Michael C.; Taylor, Stephen J.C.; Chaplin, David A.; McCague, Raymond Tetrahedron Letters, 2001 , vol. 42, # 7 p. 1347 - 1350
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Citation Number: 26
Abstract
The use of both N-tert-butoxycarbonylamino-and hydroxyl-directed hydrogenation methodology to yield essentially single diastereomers of 3-(tert-butoxycarbonylamino)-4- hydroxycyclopentanecarboxylic acid methyl esters and 3-(tert-butoxycarbonylamino) cyclopentanecarboxylic acid methyl esters is described. These results incorporate the first reported carbamate-directed hydrogenations of functionalised cyclopentenes.
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[Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705]
[Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705]
[Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705]