Organic letters

New P, N-Ferrocenyl Ligands for the Asymmetric Ir-Catalyzed Hydrogenation of Imines

MN Cheemala, P Knochel

Index: Cheemala, Murthy N.; Knochel, Paul Organic Letters, 2007 , vol. 9, # 16 p. 3089 - 3092

Full Text: HTML

Citation Number: 83

Abstract

The Ir-catalyzed enantioselective hydrogenation of various N-(3, 5-dimethyl-4-methoxy) phenylimines was performed under mild conditions in the presence of new P, N-ferrocenyl iridium complexes leading to (R)-N-(3, 5-dimethyl-4-methoxy) phenylamines in high yields and enantioselectivities (up to 99%). These chiral aryl amines can be readily deprotected using Ce (NH4) 2 (NO3) 6.

Related Articles:

Enantioselective reduction of ketoxime ethers with borane–oxazaborolidines and synthesis of the key intermediate leading to (S)-rivastigmine

[Pakulski, Marcin M.; Mahato, Sanjit K.; Bosiak, Mariusz J.; Krzeminski, Marek P.; Zaidlewicz, Marek Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 716 - 721]

Resolution of 1-arylalkylamines with 6-(1, 2: 3, 4-di-O-isopropylidene-α-d-galactopyranosyl) hydrogen phthalate

[Mereyala, Hari Babu; Fatima, Liyakat; Pola, Pallavi Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 585 - 587]

Nickel Nanoparticles as Racemization Catalysts for Primary Amines

[Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E. European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628]

Asymmetric Synthesis of Nonracemic Primary Amines via Spiroborate-Catalyzed Reduction of Pure (E)-and (Z)-O-Benzyloximes: Applications toward the Synthesis of …

[Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327]

Enantioselective reduction of ketoxime ethers with borane–oxazaborolidines and synthesis of the key intermediate leading to (S)-rivastigmine

[Pakulski, Marcin M.; Mahato, Sanjit K.; Bosiak, Mariusz J.; Krzeminski, Marek P.; Zaidlewicz, Marek Tetrahedron Asymmetry, 2012 , vol. 23, # 9 p. 716 - 721]

More Articles...