Highly Active Organocatalysts for Asymmetric anti??Mannich Reactions

…, S Sayalero, M Bahramnejad, F Cuevas…

Index: Martin-Rapun, Rafael; Fan, Xinyuan; Sayalero, Sonia; Bahramnejad, Mahboubeh; Cuevas, Felix; Pericas, Miquel A. Chemistry - A European Journal, 2011 , vol. 17, # 32 p. 8780 - 8783

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Citation Number: 32

Abstract

Aminocatalysis has undergone an intense development over the last decade, mainly due to its potential for simplifying and improving many different reactions and procedures.[1] Until now, proline-derived catalysts account for most applications in this field. These species are generally derived from natural l-proline or trans 4-hydroxyproline, and therefore the functionalization pattern of the pyrrolidine ring appears somehow restricted to a 2-or 2, 4- ...