Nitrile-Promoted Alkene Epoxidation with Urea–Hydrogen Peroxide (UHP)

L Ji, YN Wang, C Qian, XZ Chen

Index: Ji, Li; Wang, Ya-Na; Qian, Chao; Chen, Xin-Zhi Synthetic Communications, 2013 , vol. 43, # 16 p. 2256 - 2264

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Citation Number: 9

Abstract

An efficient method for alkene epoxidation has been studied systematically using benzonitrile and the complex urea–hydrogen peroxide (UHP), which is an anhydrous form of hydrogen peroxide and has the potential to release hydrogen peroxide in a controlled manner and thus avoid the need to slowly add aqueous H 2 O 2 to the reaction mixture. The absence of water in the reaction media was also beneficial, because it minimized undesired reactions of the oxidized ...