New and efficient method for esterification of carboxylic acids with simple primary and secondary alcohols using cerium (IV) ammonium nitrate (CAN)

WB Pan, FR Chang, LM Wei, MJ Wu, YC Wu

Index: Pan, Wen-Bin; Chang, Fang-Rong; Wei, Li-Mei; Wu, Ming-Jung; Wu, Yang-Chang Tetrahedron Letters, 2003 , vol. 44, # 2 p. 331 - 334

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Citation Number: 42

Abstract

The esterification of phenylacetic acids and cis-oleic acid with primary and secondary simple alcohols, which also act as solvents using cerium (IV) ammonium nitrate (CAN) at room temperature gave phenylacetates and methyl (9Z)-octadec-9-enoate. The reactions, which occur under relatively mild conditions, afforded the desired products in good to excellent yields.