Barium nitrate catalyzed one pot synthesis of 1, 4??dihydropyridines under solvent free conditions at room temperature

M Sharma, N Agarwal, DS Rawat

Index: Sharma, Mukul; Agarwal, Nisha; Rawat, Diwan S. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 3 p. 737 - 739

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Citation Number: 13

Abstract

4-Substituted-1, 4-dihydropyridines (1, 4-DHPs) exhibit wide variety of biological activities such as cardiovascular, vasodilator, bronchodilator, antiatherosclerotic, antitumour, antidiabetic, hepatoprotective, geroprotective, antituberculosis, calcium channel blocker activity, and NO releasing activity [1-5]. DHP based drugs such as nifedipine, nicardipine, amlodipine and many others are used for the treatment of hypertension and cerebrocrast; ...