Synthesis, characterization and antimicrobial studies of a few novel thiazole derivatives

AS Praveen, HS Yathirajan, B Narayana…

Index: Praveen, Aletti S.; Yathirajan, Hemmige S.; Narayana, Badiadka; Sarojini, Balladka K. Medicinal Chemistry Research, 2014 , vol. 23, # 1 p. 259 - 268

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Abstract

Abstract A series of novel N-[4-(substituted)-1, 3-thiazol-2-yl]-2-(substituted) acetamide (9a– m) and methyl 2-(2-(2-(substituted) acetamido) thiazol-4-yl) acetate (9n–o) derivatives have been synthesized and compounds were characterised by spectral and analytical studies. All compounds were screened for their in vitro antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia by disc ...