Industrial synthesis of Maxacalcitol, the antihyperparathyroidism and antipsoriatic vitamin D3 analogue exhibiting low calcemic activity

H Shimizu, K Shimizu, N Kubodera…

Index: Organic Process Research and Development, , vol. 9, # 3 p. 278 - 287

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Citation Number: 19

Abstract

... Organic Process Research & Development. ... Org. Process Res ... additive to transform it into the tertiary alcohol 12 (Scheme 2). We therefore explored a more practical procedure and have developed an alternative procedure without employing the Michael addition procedure in the ...