Synthesis and antiviral activity of various 3'-azido analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV)

…, JY Guo, RF Schinazi, CK Chu, JN Xiang…

Index: Lin, Tai-Shun; Guo, Ji-Yu; Schinazi, Raymond F.; Chu, Chung K.; Xiang, Jia-Ning; Prusoff, Willian H. Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 336 - 340

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Citation Number: 122

Abstract

28 cure, its ability to prolong life of AIDS patients, in spite of bone marrow suppression observed in some patients, has encouraged the evaluation of other AZT, as well as several other nucleoside analogues that are inhibitory to HIV-1 in vitro, was finst synthesized by Honvitz et al. 143