Synthesis of unusual perfluorocarbon ethers and amines containing bulky fluorocarbon groups: new biomedical materials

HN Huang, DF Persico, RJ Lagow…

Index: Huang, Hsu-Nan; Persico, Daniel F.; Lagow, Richard J.; Clark, Leland C. Journal of Organic Chemistry, 1988 , vol. 53, p. 78 - 85

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Citation Number: 30

Abstract

In the last two decades, there has been intense interest in using perfluorochemicals (PFCS) as “artificial blood”.'Perfluorinated ethers and amines generally form mor3 stable PFCS- based emulsions than do perfluorinated alkanes. 2 However, previous animal studies have indicated that due to some kind of interaction with liver tissues, possibly baselike interactions, perfluorinated amines or ethers exhibit extremely long or infinite retention in ...