Synthesis and biological activity of bis-thiosemicarbazones of 3-ethoxy-2-oxobutyraldehyde and their complexes with Cu (II)

…, BT Garibdzhanyan, EA Mironov, ME Vol'pin

Index: Dilanyan, E. R.; Ovsenyan, T. R.; Arsenyan, F. G.; Garibdzhanyan, B. T.; Mironov, E. A.; Vol'pin, M. E. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 7 p. 491 - 494 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 7 p. 835 - 839

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Abstract

With the aim of obtaining new derivatives of KTS and establishing the influence of structural modifications of KTS on antitumor activity, we have carried out the synthesis and have studied the biological activity of substituted bis-thiosemicarbazones of 3-ethoxy-2- oxobutyraldehyde and their copper complexes.