The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors
ZP Xiao, TW Ma, WC Fu, XC Peng, AH Zhang…
Index: Xiao, Zhu-Ping; Ma, Tao-Wu; Fu, Wei-Chang; Peng, Xiao-Chun; Zhang, Ai-Hua; Zhu, Hai-Liang European Journal of Medicinal Chemistry, 2010 , vol. 45, # 11 p. 5064 - 5070
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Citation Number: 53
Abstract
Some pyrogallol and catechol derivatives were synthesized, and their urease inhibitory activity was evaluated by using acetohydroxamic acid (AHA), a well known Helicobacter pylori urease inhibitor, as positive control. The assay results indicate that many ...