Tetrahedron letters

A facile preparation of N-protected indolaldehydes using a modified Hass procedure

AK Mohanakrishnan, R Balamurugan, N Ramesh

Index: Mohanakrishnan, Arasambattu K.; Balamurugan, Ramalingam; Ramesh, Neelamegam Tetrahedron Letters, 2005 , vol. 46, # 47 p. 8189 - 8193

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Citation Number: 8

Abstract

Indolaldehydes are crucial intermediates for the synthesis of several indole alkaloids. 1 While indole-3-carboxaldehyde can be prepared easily under conventional Vilsmeier formylation conditions, aldehydes at other positions of the indole ring are not easily accessible. Several methods have been developed for the synthesis of indolaldehydes and most are not scalable to any reasonable extent. ... Traditionally, indolaldehydes have been prepared from the corresponding ...

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