2-Guanidinoquinazolines

LF Theiling, RL McKee

Index: Theiling; McKee Journal of the American Chemical Society, 1952 , vol. 74, p. 1834

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Citation Number: 7

Abstract

A study of the preparation of numerous heterocyclic compounds carrying guanidine substituents has been initiated in this Laboratory. The 2-guanidinoquinazolines are felt to be of special interest since, when appropriately substituted, they embody the skeleton present in Paludrine. Initial attempts at preparation from Z-aminoquinazolines were abandoned when these compounds were found to resist the action of cyanogen bromide, Cyanamides ...