Synthese Simple des Analogues Fluores, Phosphones ou Sulfones de L'Acide Aspartique

…, C Denier, M Mulliez, WT De Lima

Index: Bijeire, Laurent; Denier, Colette; Mulliez, Michel; De Lima, Waldir Tavares Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 4 p. 881 - 891

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Citation Number: 4

Abstract

Two stable hemiaminals, N acylated by the p-nitrobenzoyl or Boc group and each substituted by the difluorocarboxylethylester moiety, were obtained in a single step from the corresponding ethylhemiacetal. The Boc compound, after acylation by trifluoroacetic anhydride followed by in situ reaction either with trimethylsilylated derivatives of cyanide or diethylphosphite, or with sodium sulfite, led to the protected carboxylic, phosphonic, and ...