Design, synthesis and evaluation of 7-azaindazolyl-indolyl-maleimides as glycogen synthase kinase-3β (GSK-3β) inhibitors

Q Ye, Y Shen, Y Zhou, D Lv, J Gao, J Li, Y Hu

Index: European Journal of Medicinal Chemistry, , vol. 68, p. 361 - 371

Full Text: HTML

Citation Number: 7

Abstract

... European Journal of Medicinal Chemistry. ... a ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of ... C, 61%; (f) Pd(PPh 3 ) 2 Cl 2 , LiCl, toluene, 100 °C, 55%; (g) NH 4 OAc, 140 °C, 86%; (h) CH 3 NH 2 , CH 3 OH, rt, 83%; (i) 5 mol/L KOH, EtOH, 30–35 °C, 70%; (j) R–NH 2 ...