The Journal of Organic Chemistry

Potential Cancerocidal Agents. II. Synthesis of 6, 7-Methylenedioxycarbostyril1

GR PETTIT, MV Kalnins

Index: Pettit,G.R.; Kalnins,M.V. Journal of Organic Chemistry, 1960 , vol. 25, p. 1365 - 1367

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Citation Number: 4

Abstract

During the course of a continuing search for a substance with useful antitumor activity, it was desirable to prepare 6, 7-methylenedioxycarbostyril (I) for biological evaluation. 2 Although the synthesis of 6, 7-methylenedioxycarbostyril (I) had been reported by both Narang3 and B ors~ he,~ certain inconsistencies made questionable the result of each procedure. Reduction of 3, 4-methylenedioxy-6-nitrocinnamic acid (Ha) with