Tetrahedron

A novel way to chiral 2-oxazolidinones: selenium-catalyzed cyclocarbonylation of 2-aminoethanols

P Li, X Yuan, S Wang, S Lu

Index: Li, Peng; Yuan, Xiaohua; Wang, Shudong; Lu, Shiwei Tetrahedron, 2007 , vol. 63, # 50 p. 12419 - 12423

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Citation Number: 20

Abstract

Selenium-catalyzed cyclocarbonylation of 2-aminoethanols with CO under atmospheric pressure at 30° C afforded 2-oxazolidinones in excellent yields without any other co-catalyst. The method was then applied to the syntheses of chiral 2-oxazolidinones and no racemization was detected.

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