The Journal of organic chemistry

Tert-butylsulfonyl (Bus), a new protecting group for amines

P Sun, SM Weinreb, M Shang

Index: Sun, Pu; Weinreb, Steven M.; Shang, Maoyu Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8604 - 8606

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Citation Number: 118

Abstract

Sulfonyl groups have had a long history in protection of amines and other nitrogeneous functionality. 1 One of the most attractive features of sulfonamides, their stability to a wide array of reaction conditions, has commonly proven a liability, since removal is oftentimes problematic in highly functionalized, sensitive substrates. In recent years the arsenal of N- sulfonyl protecting groups has been improved by addition of new varieties amenable to ...

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