One-pot, solvent-free synthesis of α-aminonitriles under catalysis by magnesium bromide ethyl etherate
MM Mojtahedi, MS Abaee…
Index: Mojtahedi, Mohammad M.; Abaee, M. Saeed; Abbasi, Hasean Canadian Journal of Chemistry, 2006 , vol. 84, # 3 p. 429 - 432
Full Text: HTML
Citation Number: 25
Abstract
A three-component, efficient, and facile procedure has been developed for the synthesis of α- aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds. Key words: catalyzed Strecker's reaction, α- ...
Related Articles:
The decarboxylative strecker reaction
[Das, Deepankar; Richers, Matthew T.; Ma, Longle; Seidel, Daniel Organic Letters, 2011 , vol. 13, # 24 p. 6584 - 6587]
Redox-Neutral α-Cyanation of Amines
[Ma, Longle; Chen, Weijie; Seidel, Daniel Journal of the American Chemical Society, 2012 , vol. 134, # 37 p. 15305 - 15308]
Redox-Neutral α-Cyanation of Amines
[Ma, Longle; Chen, Weijie; Seidel, Daniel Journal of the American Chemical Society, 2012 , vol. 134, # 37 p. 15305 - 15308]
Orthoamide, XXXIII. Beiträge zur Chemie von Bis (dialkylamino) acetonitrilen
[Kantlehner, Willi; Baur, Richard; Bredereck, Hellmut Liebigs Annalen der Chemie, 1980 , # 3 p. 358 - 371]