Journal of the American Chemical Society

The Synthesis of Potential Antimalarials. Some 2-Substituted 8-(3-Diethylaminopropylamino)-quinolines1

K Mislow, JB Koepfli

Index: Mislow; Koepfli Journal of the American Chemical Society, 1946 , vol. 68, p. 1553,1555

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Citation Number: 6

Abstract

Aiig., 1Mfi SUBSTITUTED 8- (~-~I~~TIIYLAMINOPROI'YIAI!~INO) ... S I IC H+ I1 C f I: N (C:€ i 5 2 0 1 I dicthylarniiio - 2 - Iivc~ro?cvi,rojivlalriiIlo) - (i - ineth- osyqiiinoli iic was prcpared. ... Experimental 8-(3-Diethylaniino-2-hydroxy-propylamino) -5,6-dimeth- oxyq~inoline.~-To molten 5,6-dimethoxy-8-aminoquino- line (20.4 g.) \vas added dropwise over a period of three hoiirs, l-diethylaniino-2,3-epoxypropane (14.0 g.) . The temperature was maintained at ...