Santacruzamate A, a potent and selective histone deacetylase inhibitor from the panamanian marine Cyanobacterium cf. Symploca sp.
CM Pavlik, CYB Wong, S Ononye…
Index: Chen, Xiaofang; Wang, Li; Du, Yu; Wu, Yanbin; Jia, Xiaojian; Yang, Yuan; Hong, Bin Molecules, 2011 , vol. 16, # 11 p. 9178 - 9193
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Abstract
... a particular emphasis on the discovery of antiparasitic and anticancer lead molecules.(18-20 ... and RP high-performance liquid chromatography (HPLC) and yielded a single molecule, santacruzamate A ... By HRESIMS, a [M + H] + peak consistent with a molecular formula of C 15 ...
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