Tetrahedron Letters

Optimized Liebeskind–Srogl coupling reaction between dihydropyrimidines and tributyltin compounds

Q Sun, F Suzenet, G Guillaumet

Index: Sun, Qi; Suzenet, Franck; Guillaumet, Gerald Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3473 - 3476

Full Text: HTML

Citation Number: 9

Abstract

We developed an optimized Liebeskind–Srogl reaction in order to synthesize potentially biologically active 2-aryl-1, 4-dihydropyrimidines. The pallado-catalyzed cross-coupling reaction between dihydropyrimidines and tributyltin derivatives appears particularly efficient