Alicyclic alkylamines and alkanolamines

A Burger, RT Standridge, NE Stjernström…

Index: Burger,A. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, p. 517 - 534

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Citation Number: 8

Abstract

Alicyclic structures carrying alkylamine chains have been the subject of a number of pharmacodynamic~ tudies, l-~ especially for their effect on blood pressure. By comparison with their aromatic prototypes, such alicyclic compounds show less activity and higher toxicity. 2 Cyclohexenyl, cyclohexyl and cyclopentyl derivatives were of the same general order of lowered activity. Branching of the side chain increased duration of action, in ...