Indium triflate catalyzed peracetylation of carbohydrates

…, LC Helland, SF Colvin, JR Twitchell, MJ Cloninger

Index: Bizier, Nicholas P.; Atkins, Shannon R.; Helland, Luke C.; Colvin, Shane F.; Twitchell, Joseph R.; Cloninger, Mary J. Carbohydrate Research, 2008 , vol. 343, # 10-11 p. 1814 - 1818

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Citation Number: 28

Abstract

Peracetylation is a very common protection strategy that is widely implemented in carbohydrate synthesis. Here, a method for the peracetylation of carbohydrates using catalytic In (OTf) 3 in neat acetic anhydride is reported. In (OTf) 3 has low toxicity and is mild and water tolerant, and the reactions are high yielding and efficient. Details regarding the scope and mechanism of the reaction are briefly discussed.

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