Benzimidazoles from preformed imidazoles. Novel approach
HJJ Loozen, EF Godefroi
Index: Loozen,H.J.J.; Godefroi,E.F. Journal of Organic Chemistry, 1973 , vol. 38, # 20 p. 3495 - 3497
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Citation Number: 14
Abstract
Benzimidazolcs arc traditionally synthcsizrd by ultimato construct'ion of the imidazolc moictt).,\ vh (trc> b). the prcroquisitc. o-ph (: ri!. lcric~ diamincs arc: cyclizod with carboxylic acids and/or d (1rivat ivw thoreof. An altcrnativc asscmbl~., commmcing with prrformcd and suitahly functionalimd imidazolcs, has, to tlic best of our lmon-lcdgtt, hitherto cwapc! d attcntion. Such an approach is 1ic: rc: ivit'h illustrated. It is, by its natur (', comp1ornc: ntarJ. ...
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[Loozen,H.J.J. et al. Journal of Organic Chemistry, 1975 , vol. 40, p. 892 - 894]